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When combined with opioids, it becomes powerful enough to be used in more severe pain, including cancer pain and pain after surgery

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Cortisol inhibits the activities of 5- and 6-desaturases, reducing the synthesis of -3 long-chain polyunsaturated fatty acids (LCPUFAs), such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid (AA)

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Blots shown are representative of three or more independent experiments, with specific repeats detailed in each figure legend and shown and quantified in the Source data file